| High dose methotrexate in adult Egyptian patients with hematological malignancies: impact of ABCB1 3435C> T rs1045642 and MTHFR 677C> T rs1801133 polymorphisms on toxicities …
AHIM Ebid, A Hossam, MM El Gammal, S Soror, NOM Mangoud, …
Journal of Chemotherapy, 1-10
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| Impedimetric Sensors for Cyclocreatine Phosphate Determination in Plasma Based on Electropolymerized Poly(o-phenylenediamine) Molecularly Imprinted …
IF Abo-Elmagd, AM Mahmoud, MA Al-Ghobashy, M Nebsen, NS El Sayed, …
ACS omega 6 (46), 31282-31291
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| Restoring NK cells functionality via cytokine activation enhances cetuximab-mediated NK-cell ADCC: A promising therapeutic tool for HCC patients
S Mahgoub, H Abosalem, M Emara, N Kotb, A Maged, S Soror
Molecular Immunology 137, 221-227
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| Interrupted Crosstalk between Natural Killer Cells and Anti-epidermal Growth Factor Receptor: A Possible Role in Hepatocellular Carcinoma Treatment Failure
H Abosalem, S Mahgoub, M Emara, N Kotb, S Soror
Current Cancer Drug Targets 21 (7), 601-607
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| Author Correction: Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo
S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, AA Khweek, …
Scientific Reports 11 (1), 1-3
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| Imidazole-based compounds as hepatitis C virus inhibitors
ME El-Araby, AM Omar, MA El-Faky, SHA Soror, MT Khayat, HZ Asfour, …
US Patent 10,959,987
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| Chitinase 3‐like‐1, Tolloid‐like protein 1, and intergenic gene polymorphisms are predictors for hepatocellular carcinoma development after hepatitis C virus eradication by …
NOM Mangoud, SA Ali, M El Kassas, SH Soror
IUBMB life 73 (2), 474-482
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| Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo
S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, A Abu Khweek, …
Scientific reports 11 (1), 1-20
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| Elevated Expression of MiR-17 in Microglia of Alzheimer’s Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation
S Estfanous, KP Daily, M Eltobgy, NP Deems, MNK Anne, K Krause, …
Frontiers in immunology, 2839
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| Revealing the potential application of EC-synthetic retinoid analogues in anticancer therapy
MR Abdelaal, SH Soror, MR Elnagar, H Haffez
Molecules 26 (2), 506
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| Composition and method for treating a patient having liver cirrhosis
ME El-Araby, AM Omar, MA El-Faky, SHA Soror, MT Khayat, HZ Asfour, …
US Patent App. 16/986,706
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| Compounds for inhibiting NS3 and compositions containing the inhibited protein
ME El-Araby, AM Omar, MA El-Faky, SHA Soror, MT Khayat, HZ Asfour, …
US Patent 10,821,096
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| Targeting NUPR1 for Cancer Treatment: A Risky Endeavor
S Mansour, SA Ali, S Nofal, SH Soror
Current Cancer Drug Targets 20 (10), 768-778
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| Peptide inhibitors of hcv ns3/4a protease comprising non-proteinogenic amino residues
ME El-Araby, AM Omar, MA El-Faky, SHA Soror, MT Khayat, HZ Asfour, …
US Patent App. 16/371,610
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| Synthetic bulky NS4A peptide variants bind to and inhibit HCV NS3 protease
ME El-Araby, AM Omar, SH Soror, ST Arold, MT Khayat, HZ Asfour, …
Journal of advanced research 24, 251-259
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| Role of Diosmin in protection against the oxidative stress induced damage by gamma-radiation in Wistar albino rats
S Mahgoub, AO Sallam, HKA Sarhan, AAA Ammar, SH Soror
Regulatory Toxicology and Pharmacology 113, 104622
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| Histone H3K27M mutation overrides histological grading in pediatric gliomas
A Mosaab, M El-Ayadi, EN Khorshed, N Amer, A Refaat, M El-Beltagy, …
Scientific reports 10 (1), 1-9
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| 1H-imidazole-2, 5-dicarboxamides as ns4a peptidomimetics: Identification of a new approach to inhibit hcv-ns3 protease
AM Omar, MA Elfaky, ST Arold, SH Soror, MT Khayat, HZ Asfour, …
Biomolecules 10 (3), 479
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| Tumorigenesis Tumor Supression
RL Akshaya, M Rohini, N Selvamurugan, SMA Mansour, SA Ali, S Nofal, …
Current Cancer Drug Targets 20 (10), 729
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| Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion
R Abskharon, F Wang, A Wohlkonig, J Ruan, S Soror, G Giachin, …
PLoS pathogens 15 (12), e1008139
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| A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR
A Tanina, A Wohlkönig, SH Soror, M Flipo, B Villemagne, H Prevet, …
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (3), 248-258
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| Evaluation of novel pyrrolopyrimidine derivatives as antiviral against gastroenteric viral infections
MS Mohamed, AI Sayed, MA Khedr, S Nofal, SH Soror
European Journal of Pharmaceutical Sciences 127, 102-114
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| Inflammasome genes’ polymorphisms in Egyptian chronic hepatitis C patients: Influence on vulnerability to infection and response to treatment
SZK Estfanous, SA Ali, SM Seif, SHA Soror, DHA Abdelaziz
Mediators of Inflammation 2019
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| The influence of SLC22A1 rs622342 and ABCC8 rs757110 genetic variants on the efficacy of metformin and glimepiride combination therapy in Egyptian patients …
AHIM Ebid, M Ehab, A Ismail, S Soror, MA Mahmoud
Journal of Drug Assessment 8 (1), 115-121
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| Correction to Discovery, Structure–Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors
A Joncour, N Desroy, C Housseman, X Bock, N Bienvenu, L Cherel, …
Journal of Medicinal Chemistry 61 (9), 4270-4270
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| Discovery, Structure–Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors
A Joncour, N Desroy, C Housseman, X Bock, N Bienvenu, L Cherel, …
Journal of Medicinal Chemistry 60 (17), 7371-7392
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| Fragment-based design, synthesis, and binding of non-peptide mimics of NS4A and their binding to HCV NS3/4A protease
M El-Araby, A Omar, M Khayat, S Soror, S Arold, M El-Faky, E Elalem, …
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252
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| Design, synthesis, assessment, and molecular docking of novel pyrrolopyrimidine (7-deazapurine) derivatives as non-nucleoside hepatitis C virus NS5B polymerase inhibitors
MS Mohamed, AI Sayed, MA Khedr, SH Soror
Bioorganic & Medicinal Chemistry 24 (9), 2146-2157
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| Novel antiviral compounds against gastroenteric viral infections
MS Mohamed, RH Abd El‐Hameed, AI Sayed, SH Soror
Archiv der Pharmazie 348 (3), 194-205
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| Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking …
B Villemagne, M Flipo, N Blondiaux, C Crauste, S Malaquin, F Leroux, …
Journal of medicinal chemistry 57 (11), 4876-4888
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| Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody
RNN Abskharon, G Giachin, A Wohlkonig, SH Soror, E Pardon, …
Journal of the American Chemical Society 136 (3), 937-944
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| High-resolution structure of a papaya plant-defence barwin-like protein solved by in-house sulfur-SAD phasing
J Huet, EJ Teinkela Mbosso, S Soror, F Meyer, Y Looze, R Wintjens, …
Acta Crystallographica Section D: Biological Crystallography 69 (10), 2017-2026
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| Expression, Purification, Characterization, and Solution Nuclear Magnetic Resonance Study of Highly Deuterated Yeast Cytochrome c Peroxidase with Enhanced …
AN Volkov, A Wohlkonig, SH Soror, NAJ Van Nuland
Biochemistry 52 (13), 2165-2175
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| Expression, Purification, Characterization, and Solution NMR Study of Highly‐Deuterated Recombinant Yeast Cytochrome c Peroxidase with Enhanced Solubility
O Volkov, A Wohlkönig, S Soror, N Van Nuland
Biochemistry 52 (13), 2166-2175
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| A novel expression system for production of soluble prion proteins in E. coli
RNN Abskharon, S Ramboarina, H El Hassan, W Gad, MI Apostol, …
Microbial Cell Factories 11 (1), 1-11
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| Course Abstracts
RNN Abskharon, A Wohlkonig, S Soror, E Pardon, H Remaut, …
Biophysics and Structure to Counter Threats and Challenges, 142
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| Nanobody-stabilize the crystal structure of full-length human PrP
R Abskharon, S Soror, G Giachin, E Pardon, H El Hassan, G Legname, …
Prion 6 (S), 115-115
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| Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands
X Carette, N Blondiaux, E Willery, S Hoos, N Lecat-Guillet, Z Lens, …
Nucleic acids research 40 (7), 3018-3030
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| Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1, 2, 4-oxadiazole EthR inhibitors
M Flipo, M Desroses, N Lecat-Guillet, B Villemagne, N Blondiaux, …
Journal of medicinal chemistry 55 (1), 68-83
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| A novel expression system for production of soluble prion proteins in E. coli.
S Ramboarina, W Gad, MI Apostol, G Giachin, G Legname, J Steyaert, …
Microbial Cell Factories 11 (1)
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| Combining in-situ proteolysis and microseed matrix screening to promote crystallization of PrPc-nanobody complexes
RNN Abskharon, SH Soror, E Pardon, H El Hassan, G Legname, …
Protein engineering, design & selection 24 (9), 737-741
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| Crystallization and preliminary X-ray diffraction analysis of kanamycin-binding β-lactamase in complex with its ligand
K Van de Water, SH Soror, A Wohlkonig, NAJ van Nuland, AN Volkov
Acta Crystallographica Section F: Structural Biology and Crystallization …
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| Nanobody-Assisted Crystallization of Human and Mouse Prion Proteins
R Abskharon, S Soror, E Pardon, H El Hassan, G Legname, J Steyaert, …
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| Crystallization and preliminary X-ray diffraction analysis of a specific VHH domain against mouse prion protein
RNN Abskharon, SH Soror, E Pardon, H El Hassan, G Legname, …
Acta Crystallographica Section F: Structural Biology and Crystallization …
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| A llama-derived gelsolin single-domain antibody blocks gelsolin–G-actin interaction
A Van den Abbeele, S De Clercq, A De Ganck, V De Corte, B Van Loo, …
Cellular and molecular life sciences 67 (9), 1519-1535
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| Mining the genome sequence for novel enzyme activity: characterisation of an unusual member of the hormone-sensitive lipase family of esterases from the genome of Streptomyces …
SH Soror, R Rao, J Cullum
Protein Engineering, Design & Selection 22 (6), 333-339
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| A cold-active esterase of Streptomyces coelicolor A3(2): from genome sequence to enzyme activity
SH Soror, V Verma, R Rao, S Rasool, S Koul, GN Qazi, J Cullum
Journal of Industrial Microbiology and Biotechnology 34 (8), 525-531
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| Characterisation of esterase genes in the genomes of Streptomyces coelicolor A3 (2) and Streptomyces avermitilis
S Soror
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| Cloning and Expression of Lipase Genes from Streptomyces Coelicolor A3 (2)
S Soror
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| Is cystatin C a powerful predictor of cardiovascular diseases in patients with type 2 diabetes mellitus?(Study on Egyptian patients)
H Rafat, SH Soror, Z Hassan, A Ismaail
Journal of Applied Pharmaceutical Science, 54-58
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| Can NLRP3 gene polymorphism in Egyptian chronic hepatitis C patients affect the degree of liver fibrosis?
SZK Estfanous, SM Seif, SHA Soror, DHA Abdelaziz
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